Guest editor for a Methods issue (a companion journal to Methods in Enzymology) entitled “Humanized Antibodies and Their Applications” (May 2005).Editorial Board, mAbs journal (2008-present).Member of Industrial Advisory Board, Institute for Applied Life Sciences (IALS), University of Massachusetts, Amherst (2016-present).Member of Scientific Advisory Board of the Development Center for Biotechnology (DCB) of Taiwan, a government-sponsored nonprofit organization (2014-present).Professional Appointments and Activities.National Taiwan University, Taipei, Taiwan, R. In addition, he has helped build hundreds of biologics in research and development with >80 programs moved into clinical development. Herren is also a co-inventor for inebilizumab and anifrolumab. (7) anti-IL-13 antibody (Adbry™ tralokinumab) for atopic dermatitis. (5) anti-type I interferon receptor antibody (Saphnelo™, anifrolumab) for systemic lupus erythematosus (6) Evusheld™ (tixagevimab and cilgavimab), long-acting antibody combination for both prevention and treatment of COVID-19. His work has led to seven market approved biologics: (1) anti-PD-L1 antibody (Imfinzi® durvalumab) for cancer treatment (2) anti-IL-5α receptor antibody (Fasenra® benralizumab) for severe eosinophilic asthma treatment (3) anti-CD22 immunotoxin (LumoxitiTM moxetumomab pasudotox) for hairy cell leukaemia (4) anti-CD19 antibody (UPLIZNA™ inebilizumab-cdon) for the treatment of Neuromyelitis Optica Spectrum Disorder (NMOSD). Played a key role in building AstraZeneca’s and MedImmune’s biologics pipeline for cancers, respiratory diseases, autoimmune diseases, inflammation, cardiovascular and metabolic diseases, infectious diseases and CNS/pain.Was responsible for AstraZeneca’s and MedImmune’s global biologic drug discovery and technology including antibody discovery, antibody/protein engineering, antibody-drug conjugates, bi-specifics/multi-specifics, therapeutic peptides, protein scaffolds, protein sciences, proteomics/metabolomics, structural biology, in vivo expressed biologics (AAV gene therapy, cell therapy and RNA/DNA therapy), and cell line generation. 50 issued US patents related to antibody/protein therapeutics and technologies.29-year experience in biologic drug discovery and development.
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Each ETP has a unique risk profile, detailed in its prospectus, offering circular, or similar material, which should be considered carefully when making investment decisions. Tax efficiency iShares ETFs can generally help reduce tax consequences because of their strategy and structure. What is a commodity ETF A commodity ETF is an exchange-traded fund that invests in physical commodities such as agricultural products, energy sources and metals. The degree of liquidity can vary significantly from one ETP to another and losses may be magnified if no liquid market exists for the ETP's shares when attempting to sell them. iShares’ range of ETFs makes it convenient to invest for the long term, minimize risk, and match financial goals with what matters to you. An ETP may trade at a premium or discount to its net asset value (NAV) (or indicative value in the case of exchange-traded notes). The return of an index ETP is usually different from that of the index it tracks because of fees, expenses, and tracking error. ETPs that use derivatives, leverage, or complex investment strategies are subject to additional risks. ETPs that target a small universe of securities, such as a specific region or market sector, are generally subject to greater market volatility, as well as to the specific risks associated with that sector, region, or other focus. iShares Diversified Commodity Swap UCITS ETF (DE) NAV as of 15.May.2023 EUR 24.46 52 WK: 23.83 - 32.43 1 Day NAV Change as of 15.May.2023 0.28 (1.14) NAV Total Return as of 15.May.2023 YTD: -9.66 Overview Performance Fund Facts Holdings Literature Important Information: Capital at Risk. Foreign securities are subject to interest rate, currency exchange rate, economic, and political risks, all of which are magnified in emerging markets. Exchange-traded products (ETPs) are subject to market volatility and the risks of their underlying securities, which may include the risks associated with investing in smaller companies, foreign securities, commodities, and fixed income investments. ttered your dreams I know the drill and I know the truth And it kills 15 12.Triple Platinum this is not a fire drill Real trap nigga live like I'm triple platinum Marble the floors and put gold on 16 1.American Muscle ibs or they work on drill rigs Where you might just lose a limb or get killed here And it's hard but it's 17 18.Los Minions Minions Una cua drilla de morros Anda fuerte en Culiacán Se auto nombraron'Los Minions' Y andan dando 18 6.The Recipe y your lady love my drill Even my diamonds drippin'(Wet) Baby girl don't slip Appreciate the fan love and 19 1.Better et a nigga check us Drill the opps that's what the hittas do Fuck a bitch let her switcharoo Cop a coupe 20 8.Slave r know this isn't a drill For real Why even picket it'cause you fail to engage When you don't even realizĢ1 3.Brainwash brain As you try to drill a hole into my head so you can drain All the juices in my brain I use to create 22 3.Soltera igas tiene una escua drilla Les dicen el combo pesadilla Tienen el corazón seco vaciaron el amor por un hu 23 6.Drilling Holes Park6. thrills My niggas runnin' tip drills can't sit still Don't give a fuc 13 6.For Real led Fuck around get drilled Cut your hands if you steal Whip it up like a meal I just made me a mill' Mon 14 3.Guilty know the drill and I know the truth And it kills me Yeah I'm guilty Don't come near me The one thing I'm good at is messing up somebody else. om the'Raq we the home of the drillers Comin' from the hundreds you g 2 13.HOLY GHOST to do with it over- drill When you in the field and you innocent why you over here Body count protocol th 3 15.I'M ON ONE s to be goin' on no drills nah for real Never been up to my record label never knew the deal Said she wan 4 19.BLOKE rear no le gusta el drill La tengo sudando como pollo al grill No queremos a los kiko' en este carril Aqu 5 5.Hollywood Gangsta s out there on that drill shit Yeah Yeah Ayo yo let me try this shit out right here The scars of martyrsĦ 1.Narrow Road night that I did my drill'Cause ayy we are not the same(We are not the same) I got murder murder murder r 7 5.Million Pieces s loving it's not a drill Don't look outside The world is ending Faster faster faster faster fast The ech 8 6.Take One e a pussy nigga the drill I be lovin' when we vibin' I be lovin' when we chill And that pussy so damn goo 9 9.YSIV he Middle East they drill me If you let your guard down then some people'll steal me I knew these two dud 10 13.CAN'T SAY baby she just wanna drill The vibe's too wavy it's too hard to kill Gotta watch out where you go'cause sh 11 1.A Little More t's the same Take a drill right to my brain More than it did just yesterday I guess I get it now It looks 12 5.ATM nnin' tip drills can't sit still Don't give a fuck if it kills it mix well I'm only countin' Big bills big bills I fell in love with big wheel. Album ( Page Link ) Song ( Page Link ) ( Partial Lyrics ) 1 3.KEEP IT BURNIN me of the drillers I'ma buy a home then see you're home if I miss you Rubbin' on your ass but your mouth is the issue When you run for'24 I be. Despite the initiative, each material was relying on religious faith and superstition. But many of these were foolish, unreasonable and brutal. They used different inventive materials for confirmation of truth over the centuries. Mankind has found many methods to distinguish truthfulness from deception. In the history of civilization, there have been futile or incomplete attempts to discover lies and to confirm the truth. Go to Polygraph School > The history of polygraph These tensions included changing in heart rate, feelings of anxiety or nervousness, person’s signals and other more which prove to lie. Polygraphs are based on this theory that people who lie or deceive, show physiological evidence of the tension. Notwithstanding the colloquial term, the polygraph does not recognize lies. Polygraph or lie detector utilizes mostly in law enforcement agencies and police investigations in order to examine deceptive reactions of individuals. For the first time in 1921, it was used as a lie detector. Therefore, the etymology of the polygraph originated from polys “much, many” and “Graphos” writing.īut as a term, the polygraph is a device to record the alternations of distinct pulsations simultaneously. The word polygraph is literally derived from the Greek word “Polygraphos” meaning writing much. In the end, you will get familiar with the polygraph usage in different agencies and the benefits of using it. Then, it talks about the creation of polygraph idea and the theory. After a brief explanation of the title, the article will explain about the concise history of the polygraph. SonoSite has applied for patent protection for this significant advance in needle visualization technology.is the innovator and world leader in bedside and point-of-care ultrasound and an industry leader in ultra high-frequency micro-ultrasound technology and impedance cardiography equipment.A Brief Introduction to Polygraph: This article will describe the etymology, word formation and definition of the polygraph to the readers. Is the innovator and world leader in bedside and point-of-care ultrasound and an industry leader in ultra high-frequency micro-ultrasound technology and impedance cardiography equipment. VERBATIM: The Language Quarterly Vol XI No 1 1984 How about this: can you come up with a lyric rhyming choreography with stereography and cardiography? Megite Technology News: What's Happening Right Now 2009 Its line of impedance cardiography, or ICG, products allows doctors to assess the heart and underlying cardiovascular disorders.ĬardioDynamics Acquired For $10M - San Diego-based CardioDynamics, a maker of cardiography products used for non-invasive assessment of cardiac output, is being acquired for $10M by SonoSite. San Antonio Business News - Local San Antonio News | The San Antonio Business Journal 2010īased on a two-D eco- cardiography that records the heart's pumping rate, the doctor will recommend how much water you should have in a day. (is the innovator and world leader in hand-carried ultrasound and industry leader in impedance cardiography equipment. History of the Division of Medical Sciences United States National Museum Bulletin 240, Contributions from the Museum of History and Technology, paSami Khalaf HamarnehĪbout SonoSite, Inc. University of Lund at this time was the ultrasonar cardiography, developed by Helmuth Hertz and Inge Edler.Įxhibits of original galvanometers and other apparatus will trace the development of cardiography. Underworld provides nothing ground-breaking, but it looks great and Lara is still an incredibly satisfying character to take in hand. A 'previously on.' video of plot highlights is thoughtfully supplied, though. The hackneyed plot presumes you know, and care, about Lara's previous outings. It's a simple matter of shoot and shoot some more, while jumping to avoid tooth or claw. Crystal Dynamics developed the PlayStation 3, Xbox 360, and PC versions and was released in November 2008. Gunplay is the weakest element, combining point-and-shoot mechanics with dull opponents. Tomb Raider: Underworld, also known as Tomb Raider 8, is an action-adventure video game developed by Crystal Dynamics, Buzz Monkey Software, and Santa Cruz Games and was published by Eidos Interactive. It's not all dusty tombs, either: diving off your boat on the first level and swimming down to explore the sea bed provides an inspired opening that sets the tone for the whole game. Natural elements, such as ledges on cliffs, manage to look believable while still having an obvious purpose in the game. The graphics are stunning, the environments are amazingly detailed and any sense of the blocky construction of earlier titles is now gone. She looks sublime in action, too, thanks to a new animation blending system and motion-captured moves. She reacts snappily to your inputs, and you'll rarely find yourself blaming the controls for mishaps. Under your control she can jump, climb, tumble and somersault past almost any obstacle. Thankfully, Lara is an incredibly talented acrobat. You also need to assess how you're going to go about reaching the areas required. It has all of the pieces of whats to come. You have to work out what you need to do, and in what order. Tomb Raider: Underworld Great ingredients with a poor recipe Tomb Raider Underworld is an action adventure game staring lara croft after thors hammer And if youre expecting a great experience like that of Tomb Raider 2013 or Rise of the tomb raider youre just not going to get that here. Most of the levels are designed around a series of interconnected puzzles. Underworld succeeds in intertwining these three elements, making for a pleasingly varied experience. Gameplay is the usual combination of gymnastics, gunfights and exploration. Lara Croft is still video gaming's most successful heroine, with this being her ninth escapade in 12 years. The throwing mostly happens before the end of the pre-game “Star-Spangled Banner,” as few people want to have a smelly, rotting animal stuck to them for any longer than necessary. Then they smuggle the beasts inside, often using plastic wrap or tape to affix the contraband to the small of their backs, stomachs, or legs while the ushers and security guards (usually) turn a blind eye out of loyalty to the team. Fans either purchase the fish at local seafood markets or catch their own whiskered whales from the Cumberland River, which runs a few blocks from Bridgestone. But, hey, if it's good for the team, I guess we can deal with it.'')Īnd as one might reasonably expect, it’s not an easy stunt to pull off, given that it’s technically illegal to bring them into the stadium. They're huge, they're heavy, they stink, and they leave this slimy trail on the ice. (Not everyone was happy about it, though - one stadium worker tasked with cleaning them up said, “They are so gross. During the game, seemingly out of nowhere, a catfish flew over the glass onto center ice, the crowd went wild, Nashville won, and the tradition was born. Frederick Breedon/Getty Images Sportįast forward to 2002, when the Wings came to Nashville, and some inspired Preds lover decided that the team needed its own twist on the toss, this time using a staple of local cuisine. The Red Wings took home the Cup and, with hockey fans generally being superstitious types, the octopi have been raining down from the stands ever since. The practice dates back to 1952, when some Detroit rooters decided to throw an octopus onto the ice for good luck, reasoning that the eight arms of the cephalopod represented the eight wins necessary for the team to win a championship. These carpetbaggers were an important part of the initial rooting section, bringing their passion for the game to the arena, as well as their own strange habit - The Legend of the Octopus. Many wonder, “Why in the good name of Lord Stanley do the Preds faithful do this?” Well, you can blame it on Detroit.īack when the Predators launched in 1998, a large portion of the fanbase was made up of Red Wings-loving transplants who worked at the local auto plants. Believe it or not, Nashville is now an honest-to-goodness hockey town, and more and more people are learning about the diehard fans’ bizarre game-time ritual: throwing catfish onto the ice. Now all of a sudden it Only shows up in a totally different state and with exact name search. Is there something I could do to send signals to Google to show that I am in Matthews, NC?Ģ months ago my listing quit showing up at all unless you typed exact business name What could possibly cause my listing or Google to do this? I have been without my listing for a few months now and have NO calls coming in from it. If you search Locksmith Independence, KS it shows up on the maps. If you search Locksmith Matthews, NC my listing does not show up at all. Keep in mind the GMB is in Matthews, NC All my service areas and the actual map show the correct areas. Now if I search my business name under the auto populate I see it with Independence, KS on the listing. I pretty much do not have any traffic, views or calls now. Posted about my SAB listing a few weeks ago about not showing up in search only when you entered the exact name. Boyish Short Hair: To the point where a player might confuse her with a man at first.Having been trained for combat since a child, knight excels in close combat and with different weaponry. Knight with pure and righteous ways of the warrior. You can find him later on and pretend nothing happened, allowing him to join the party permanently, or you can confront him over the matter and have a battle to the death with him. He will also take some coins should they not have any healing vials on them. So Long, and Thanks for All the Gear: Once the protagonist arrives at the blood pit after recruiting him, Cahara ditches their party, taking a blue or light blue vial.The Sneaky Guy: Cahara's skills are largely based around using dirty tricks to give him an advantage or even just outright running from combat.Shell-Shocked Veteran: In his S-ending Cahara escapes the prison and is able to free his lover from her life of forced prostitution but is forever changed by his experiences and remains deathly paranoid about the inevitable return of the God of Fear and Hunger for the rest of his days.Abandoning your comrades allows the mercenary to learn Escape Plan, allowing for a greater chance of running from a battle. Screw This, I'm Outta Here: During the introduction sequence, you are given a choice to either fight to the last breath or abandon your comrades when asked what you would do in the midst of an ambush.Really Gets Around: Mentions having had many male and female lovers in the past.Not that he can truly enjoy his newfound wealth, considering the hell he's been through. Rags to Riches: If he escapes the dungeon, Cahara sells the King's Crown and becomes fabulously rich.Cahara? Most of the time he'll express unashamed enthusiasm for it.
It's only responsible for protecting communications between hosts. This tutorial is going to show you how to install SABnzbd on Debian. It’s cross-platform, available for Linux, BSD, macOS, UNIX, Windows, Synology, QNAP, and so on. It does very little to prevent being hacked. SABnzbd is a free open-source and web-based Usenet client for downloading binary content (image, audio, video, e-book, etc.) on Usenet. SSL/TLS is not 100% secure though, servers can still be attacked directly or user error (phishing, installing malware etc.). What it does more or less is confirm the identity of the party sending and receiving information, and it that changes at any point the connection will fail. SSL/TLS prevents man-in-the-middle attacks and replay attacks that sniff out sensitive information sent and received on a network. This is a bit harder to show in pictures but usually all you have to do is let the application know to use SSL when making a connection. It is also possible to use SSL to encrypt a back-end connection to a database, LDAP server, web server, etc. Here is an example of how you can deploy SSL to encrypt the front-end of several applications: Once the certificate is ready, locked, and 's time to deploy. Use multiple news servers at the same priority. SABnzbd should report a pysthone of 100.000 or higher. Slower disks like HDD and NAS have a very negative impact on downloading speed: a slower disk means slower downloads. You can access and manage SABnzbd from any device with a web browser, including iOS and Android phones and tablets. You can also tell SABnzbd to open a page in your Internet browser whenever. SABnzbd should report the speed of Incomplete and Complete at least 150 MB/s. SABnzbd 4.0.0 For Windows Downloads for other platforms Free and easy binary newsreader It runs anywhere SABnzbd runs on Windows, macOS, Unix and NAS devices. Sure sure you should generate new certificates for every new thing but does it really matter if its only going to be private? The fact that data will be encrypted is well, good enough for a home network. Usenet providers use SSL encryption but youd need to pay for a VPN service. With a (unsigned) certificate in one hand and a key in the other (sorry people with no hands), you can now encrypt everything you want.as long as it supports it. SSLShopper has a guide for these commands. PEM file was needed (Sonarr I'm looking at you!). KEY files are definitely the most popular option but I've had situations where a. There are a variety of commands available to convert your. Increasing 365 to 3650 would make it valid for 10 years. SABnzbd falls safely within the NZB downloader category. Openssl.exe req -x509 -nodes -days 365 -newkey rsa:2048 -keyout server.key -out server.crtīoth these commands will generate a certificate and key file valid for 365 days (1 year) within the directory you ran the command. Usenet providers use SSL encryption but youd need to pay for a VPN service to be protected if. I saw reviews of Alba on Chronicle and decided to celebrate my birthday there. Next time you are feeling that cranky, call in sick! We don't get out often! More Unfortunately, this time we could not bring ourselves to do it. We have been tipping 50% during the pandemic as we empathize with servers during this difficult time. We tried to instill some holiday spirit but no luck. We could not get her to crack a smile, in fact, she seemed overall annoyed with us. Now the only disappointment, the waitress was a scrooge. Drinks are big and nice too not too much alcohol that you are seeing stars. The chicken was delicious, tasty with a side of kale. The salad was delicious with a big chunk of authentic feta. Not too many little squid like pieces either, more rings just the way we like it. We started out with the calamari and Mediterranean salad. More upscale and pricey of a setting but well worth it in the food! MoreĪ holiday pandemic! How to chase away the blues of this drag of a holiday season? Head to a fancy restaurant with the whole family to instill some cheer.Īlba looked beautiful! The windows were painted with glorious snow scenes and the inside was decorated. Suitable for solo, friends, families and dates. I will for sure come here again on date night. It all paired nicely with a Chianti red wine. I highly recommend getting and order of truffle fries because they are addictive. For entrees I can recommend the Diavolo linguine and the grilled octopus. These were the best raw oysters I've ever had. I can recommend Crab cakes and raw oysters for an appetizer. I'm a big seafood lover and the raw bar/seafood options do not disappoint. The servers have always been attentive without rushing. ALBA and Zef cicchetti are part of the same restaurant so it pops up as both when you search it. It can be a bit confusing to find the main entrance as there is a big glass slide door that stays locked. nice retaurant and the other side has a bit more of a bar vibe. The two different dining areas in the interior have different vibes, one is simply a. The rooftop is very nice, with a full bar and tv, perfect for warm days. I have been here multiple times and sat in all the rooms and rooftop bar. Will definitely return to try out the other items on the menu and order another piece of the chocolate cake for dessert. For appetizers, we order the grilled octopus and calamari. We ordered the fish and chips and ribeye. Restaurant was full and she was attentive, friendly, polite and professional. Especially when she seemed to be the only one working. With this I would have rated 3 stars but because of the great service from our waitress and the food being excellent, I will rate 4 stars. The noise level was so loud you could not talk to each other in your party let alone place your order comprehensively. Had to bring up the menu on our phones from their website to actually read. Not to mention the wording on the menu was very small. Can’t read the menu with the poor lighting. Restaurants with Outdoor Seating in Quincy.Seafood Restaurants for Families in Quincy.Mexican Restaurants for Lunch in Quincy.Hotels near Quincy Quarries Reservation.Hotels near South Shore Sights and Lights Holiday Trolley Tour.Hotels near Thomas Crane Public Library.Hotels near USS Salem & United States Naval Shipbuilding Museum.Hotels near Adams National Historical Park.
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